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Comparative pharmacokinetic/pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole, in humans

✍ Scribed by M. Katashima; K. Yamamoto; Y. Tokuma; T. Hata; Y. Sawada; T. Iga


Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
701 KB
Volume
23
Category
Article
ISSN
0378-7966

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Pantoprazole (PAN) is a proton pump inhibitor that is administered as a racemic mixture. The pharmacokinetics of PAN enantiomers were investigated in extensive metabolizers (EMs) and apparent poor metabolizers (PMs) of PAN who received a single 40, 60, or 80 mg oral dose of racemic PAN as enteric-co