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Comparative mutagenicity test of three cyclophosphamides in the bone marrow of Chinese hamsters (Cricetulus griseus)

✍ Scribed by I. Stegner; A. Herwig


Book ID
113190585
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
35 KB
Volume
29
Category
Article
ISSN
0027-5107

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The potentiating effect of caffeine (1,3,7-trimethylxanthine) on chemically induced chromosome aberrations was studied in bone marrow cells of chinese hamsters, exposed to the alkylating agent cyclophosphamide. Four experimental series were performed: In the first two tests caffeine (200 mg/kg) or c