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Comparative microspectrophotometric investigation of the DNA content in cells of primary foci and metastases of malignant melanoma

✍ Scribed by G. G. Avtandilov; L. V. Chervonnaya


Publisher
Springer US
Year
1973
Tongue
English
Weight
195 KB
Volume
75
Category
Article
ISSN
0007-4888

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CDKN2A has been found mutated in melanoma families which show linkage to chromosome 9p21. In contrast, a low mutation rate has been found in melanomas, suggesting that CDKN2A might not be the first target for mutation in the development of this type of tumour. To elucidate the role of the CDKN2A gen