Phase I metabolism of ganstigmine. Rat,
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Catinella Silvia; Pelizzi Nicola; Puccini Paola; Marchetti Silvia; Zanol Margher
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Article
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2001
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John Wiley and Sons
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English
⚖ 299 KB
## Abstract Ganstigmine, a new acetylcholinesterase inhibitor, was incubated with rat liver microsomes and the resulting metabolites were identified by high‐performance liquid chromatographic/mass spectrometric (HPLC/MS) and HPLC/MS/MS analyses. The results showed the formation of eight main metabo