Disposition of methacrylonitrile in rats
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Rogelio Cavazos Jr; Mohammed Y. H. Farooqui; Wesley W. Day; Maria I. Villarreal;
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Article
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1989
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John Wiley and Sons
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English
β 429 KB
The interaction of 2['JC]methyl-2,3['JC]acrylonitrile (MeAN) with the components of blood and its disposition in male Sprague-Dawley rats has been investigated. Following an oral administration of 100 mglkg (0.5 L D ~~. 8 vCi/kg), the rats excreted 43% of the ['4C] in the urine, 15% in the feces and