𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparative immunogenicity of recombinant B domain-deleted porcine factor VIII and Hyate:C in hemophilia A mice presensitized to human factor VIII

✍ Scribed by E. T. Parker; H. N. Craddock; R. T. Barrow; P. Lollar


Book ID
109148320
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
244 KB
Volume
2
Category
Article
ISSN
1538-7933

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Influence of aggregation on immunogenici
✍ Vivek S. Purohit; C. Russell Middaugh; Sathyamangalam V. Balasubramanian πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 221 KB

Recombinant human factor VIII (rFVIII), a multidomain glycoprotein is used in replacement therapy for treatment of hemophilia A. Unfortunately, 15%-30% of the treated patients develop inhibitory antibodies. The pathogenesis of antibody development is not completely understood. The presence of aggreg

Effect of route of administration of hum
✍ Aaron Peng; Puneet Gaitonde; Matthew P. Kosloski; Razvan D. Miclea; Prashant Var πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 115 KB

Factor VIII is a multi-domain glycoprotein and is an essential cofactor in the blood coagulation cascade. Its deficiency or dysfunction causes Hemophilia A, a bleeding disorder. Replacement using exogenous recombinant Factor VIII (FVIII) is the first line of therapy for Hemophilia A. Immunogenicity,

Phosphatidylserine containing liposomes
✍ Karthik Ramani; Razvan D. Miclea; Vivek S. Purohit; Donald E. Mager; Robert M. S πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 257 KB

Factor VIII (FVIII) is a multidomain protein that is deficient in hemophilia A, a clinically important bleeding disorder. Replacement therapy using recombinant human FVIII (rFVIII) is the main therapy. However, approximately 15-30% of patients develop inhibitory antibodies that neutralize rFVIII act