Comparative genomics reveals gene-specific and shared regulatory sequences in the spermatid-expressed mammalian Odf1, Prm1, Prm2, Tnp1, and Tnp2 genes

Extended analysis of the region encompas

Extended analysis of the region encompassing the PRM1→PRM2→TNP2 domain: Genomic organization, evolution and gene identification

✍ Kramer, Jeffrey A.; Adams, Mark D.; Singh, Gautam B.; Doggett, Norman A.; Krawet 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 248 KB 👁 1 views

The human male haploid expressed protamine 1 (PRM1) →protamine 2 (PRM2) →transition protein 2 (TNP2) locus comprises a coordinately regulated multigenic domain. This region of 16p13.13 has been used as a model to address how the organization of genes and genic domains within the human genome may inf