Comparative genomics and proteomics in drug discovery

✍ Scribed by Coward, Kevin; Parrington, John

• Publisher: Taylor & Francis Group;CRC
• Year: 2007
• Tongue: English
• Leaves: 195
• Series: Experimental biology reviews.; Symposia of the Society for Experimental Biology 58
• Category: Library

✦ Synopsis

"Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programmes, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds."--Jacket.  Read more...

Abstract:

Gives an overview of how genomic and proteomic technologies make significant contributions to global drug discovery programmes, and in particular, the key role that comparative genomics and proteomics play within this strategy. This book is written by respected authorities, from both academic and pharmaceutical backgrounds.  Read more...

✦ Table of Contents

Content: Comparative genomics and drug discovery in trypanosomatids --
The practical implications of comparative kinetoplastid genomics --
The relevance of host genes in malaria --
Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics --
Discovery of novel sodium channel inhibitors : a gene family-based approach --
'Omics' in translational medicine : are they lost in translation? --
Drug-target discovery in silico : using the Web to identify novel molecular targets for drug action.

✦ Subjects

Pharmacogenomics;Proteomics;Drug development;Pharmacognosy;Pharmacogenetics;Drug Design;Genomics;methods;MEDICAL;Pharmacology;Genomik;Vergleichende Forschung;Arzneimittelentwicklung;Proteomanalyse