Comparative genomic hybridization detects losses of chromosomes 22 and 16 as the most common recurrent genetic alterations in primary ependymomas

Gain of 1q and loss of 22 are the most c

Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridisation in paediatric ependymoma

✍ Samantha Ward; Brian Harding; Peter Wilkins; William Harkness; Richard Hayward; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 220 KB

## Abstract Ependymomas are the third most common brain tumour in the paediatric population. Although cytogenetic and molecular analyses have pinpointed deletions of chromosomes 6q, 17, and 22 in a subset of tumours, definitive patterns of genetic aberrations have not been determined. In the presen