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Comparative genomic hybridization analysis of abnormalities in chromosome 21 in childhood osteosarcoma

✍ Scribed by Simone dos Santos Aguiar; Lilian de Jesus Girotto Zambaldi; Adilson Manoel dos Santos; Walter Pinto Jr.; Silvia Regina Brandalise


Book ID
113513106
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
294 KB
Volume
175
Category
Article
ISSN
0165-4608

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Comparative genomic hybridization (CGH) was used to evaluate and map genomic aberrations in 50 hepatocellular carcinomas (HCCs) from patients chronically infected with hepatitis B virus (HBV). CGH clearly detected nonrandom genomic imbalances. Losses were most prevalent on chromosome regions 4q (70%