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Comparative Genomic Hybridization Analysis Detects Frequent Over-Representation of DNA Sequences at 3q, 7p, and 8q in Head and Neck Carcinomas

โœ Scribed by N.A. Bergamo; S.R. Rogatto; R.C. Poli-Frederico; P.P. Reis; L.P. Kowalski; M. Zielenska; J.A. Squire

Book ID
114137048
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
316 KB
Volume
119
Category
Article
ISSN
0165-4608

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We used comparative genomic hybridization (CGH) to identify recurrent chromosomal imbalances in tumor DNA from 25 malignant ovarian carcinomas and two ovarian tumors of low malignant potential (LMP). Many of the carcinoma specimens displayed numerous imbalances. The most common sites of copy number