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Comparative genomic hybridization analysis detected frequent overrepresentation of chromosome 3q in squamous cell carcinoma of the lung

โœ Scribed by Chujo, Masao; Noguchi, Tsuyoshi; Miura, Takashi; Arinaga, Mitsuyuki; Uchida, Yuzo; Tagawa, Yutaka


Book ID
118570872
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
158 KB
Volume
38
Category
Article
ISSN
0169-5002

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We used comparative genomic hybridization (CGH) to identify recurrent chromosomal imbalances in tumor DNA from 25 malignant ovarian carcinomas and two ovarian tumors of low malignant potential (LMP). Many of the carcinoma specimens displayed numerous imbalances. The most common sites of copy number