Trace impurities in amphetamine sulphate were studied by a highly sensitive gas chromatographic method. The concentration of these impurities varied considerably between batches whereas the variations within the batches were usually very small. The method is used for the assignment of seizures of am
Comparative gas chromatographic analysis of narcotics : IV. Methamphetamine hydrochloride
✍ Scribed by Lars Strömberg; Hans Bergkvist; Edirisinghe A.M.K. Edirisinghe
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 589 KB
- Volume
- 258
- Category
- Article
- ISSN
- 1873-3778
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✦ Synopsis
Chemical signatures (or impurity profiles) of methamphetamine hydrochloride were displayed by gas chromatography. The analyses of samples from two series of batches showed that the inter-batch variation of signatures was significantly greater than the corresponding intra-batch variation. In many cases, this permits the establishment of common or different origins of methamphetamine seizures.
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Two cases of acute intoxication of buflomedil hydrochloride are reported. The analysis of this compound was performed by an Extrelut extraction followed by a gas chromatographic-mass spectrometric determination. Analytical parameters of linearity, reproducibility and specificity were satisfactory.