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Comparative evaluation of preclinical in vivo models for the assessment of replicating retroviral vectors for the treatment of glioblastoma

✍ Scribed by Juraj Hlavaty; Gerrit Jandl; Melissa Liszt; Helga Petznek; Marielle König-Schuster; Jenny Sedlak; Monika Egerbacher; Jakob Weissenberger; Brian Salmons; Walter H. Günzburg; Matthias Renner


Book ID
106481671
Publisher
Springer US
Year
2010
Tongue
English
Weight
502 KB
Volume
102
Category
Article
ISSN
0167-594X

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Breast cancer is an important disease site for chemopreventive intervention. The current in vim rodent models for breast cancer do not adequately approximate the human disease. Thus, we developed a new series of models based on the direct introduction of activated oncogenes into in sifu mammary duct