The efficacy of pyrimethamineisulfadoxine (I'S) and chloroquine plus chlorpheniramine, a histamine H1 receptor blocker which reverses chloroquine insensitivity in Plasmodium falciparum in vitro, was evaluated in 100 consecutive children with acute symptomatic uncomplicated falciparum malaria. Parasi
Comparative efficacy of halofantrine, chloroquine and sulfadoxine-pyrimethamine for treatment of acute uncomplicated falciparum malaria in Nigerian children
โ Scribed by C.O. Falade; L.A. Salako; A. Sowunmi; A.M.J. Oduola; P. Larcier
- Book ID
- 108368976
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 643 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0035-9203
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In the face of growing chloroquine resistance of Plasmodium falciparum, efforts to prolong the clinical usefulness of the drug have partly concentrated on its combination with potential resistance-reversing compounds. However, clinical studies on such combinations have been limited. We have compared
The cardiac effects ofhalofantrine (HF) and chloroquine plus chlorpheniramine (CQ-CP), a histamine Hi antagonist which reverses chloroquine insensitivity in Plasmodium falciparum in vitro and in vivo, were assessed in 41 children with acute svmntomatic uncomnlicated P fa&arum malaria bv electrocardi
Chlorpheniramine, a histamine HI receptor antagonist, reverses chloroquine resistance in Plasmodium falciaarum in vitro. However. the clinical sianificance of this remains unclear. We have evaluated the efficacv of chloroquine and a chloroquine-chlorbheniramine combination in 112 consecutive childre