✦ LIBER ✦
Comparative efficacy of AHU-377, a potent neprilysin inhibitor, in two rat models of volume-dependent hypertension
✍ Scribed by Laxminarayan G Hegde; Cecile Yu; Cheruvu Madhavi; Russell Araki; Jennifer Villarreal; Glenmar Obedencio; Anne Kanta; Erik Sandvick; Craig Hill; Kevin Dement; Uwe Klein; Donavon McConn; William Martin; Sharath S Hegde
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 219 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-2210
No coin nor oath required. For personal study only.
✦ Synopsis
Figure 1 Comparison of peak fall in MAP (relative to baseline; A) and 12 hour vehicle adjusted AUC MAP (B) following oral administration of AHU-377 (30 and100 mg/kg, PO) in conscious Dahl-SS and DOCA-salt hypertensive rats (n=4-7 per treatment group).