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Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the hamster, rat and guinea pig

✍ Scribed by Kevin M. Kransler; Barbara P. McGarrigle; James R. Olson


Book ID
108287375
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
193 KB
Volume
229
Category
Article
ISSN
0300-483X

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An in situ (explant tissue culture) model has been developed to study the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), hormones, and growth factors either alone or in combination. In our model system, the effect of TCDD on protein phosphorylation was greatly affected by the presence or the