𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparative clinical pharmacology of [111In]-labeled murine monoclonal antibodies

✍ Scribed by M. G. Rosenblum; J. L. Murray; L. Lamki; G. David; D. Carlo


Publisher
Springer
Year
1987
Tongue
English
Weight
694 KB
Volume
20
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The clinical pharmacology of therapeutic
✍ Lorin K. Roskos; C. Geoffrey Davis; Gisela M. Schwab πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 176 KB

## Abstract Seventeen monoclonal antibodies are currently approved in the United States for therapeutic use in organ transplantation, percutaneous coronary intervention, prophylaxis of respiratory syncytial virus disease, rheumatoid arthritis, Crohn's disease, asthma, chronic lymphocytic leukemia,

A comparative distribution study of111In
✍ Robert G. Buckley; Paul Barnett; Frances Searle; Rosamund Pedley; Joan A. Boden πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 328 KB

Conjugates of the chelating agents DTPA and TTHA with a monoclonal anti-HCG were prepared. The tissue distribution of the 111In-labeled conjugates and also 111In-citrate was studied in mice bearing human choriocarcinoma xenografts. The antibody conjugates both gave high liver and spleen radionuclide

Optimum labelling of monoclonal antibody
✍ R. R. Reilly; G. G. Ege πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 French βš– 379 KB

Monoclonal antibody 3E1.2 was coupled with the bifunctional chelate, cyclic DTPA anhydride, at molar ratios (cOTPAA:3E1.2) of 1:1, lO:l, 1OO:l and 1oOO:l. The desired substitution level of less than one mol of D"PA/bl of 3E1.2 was achieved at a molar ratio of 1O:l and a coupling efficiency of 9.9t3.