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Comparative biotransformation of morphine, codeine and pholcodine in rat hepatocytes: identification of a novel metabolite of pholcodine

✍ Scribed by Jairaj, M.; Watson, D. G.; Grant, M. H.; Gray, A. I.; Skellern, G. G.


Book ID
121190840
Publisher
Informa plc
Year
2002
Tongue
English
Weight
477 KB
Volume
32
Category
Article
ISSN
0049-8254

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Only limited studies have been reported on the disposition and pharmacokinetics of pyrazinamide (PZA) in both animals and humans. The metabolism of PZA has never been completely elucidated, consequently the metabolites of PZA, pyrazinoic acid (PA), 5-hydroxypyrazinoic acid (SHOPA), and 5-hydroxypyra