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Comparative bioassay of drugs in adjuvant-induced arthritis in rats: Flufenamic acid, mefenamic acid, and phenylbutazone

โœ Scribed by By Claude V. Winder; Lois A. Lembke; Marvin D. Stephens


Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
679 KB
Volume
12
Category
Article
ISSN
0004-3591

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The present study examined the effects of the antiparkinsonian drug budipine on dopamine synthesis and release from L-DOPA in the substantia nigra of reserpine-treated rats. Budipine (at 100 microM, but not 10 microM) applied by reverse dialysis to the nigra caused a small and significant rise in do