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Comparative antitumor studies on platinum(II) and platinum(IV) complexes containing 1,2-diaminocyclohexane

โœ Scribed by Vollano, Jean F.; Al-Baker, Salaam; Dabrowiak, James C.; Schurig, John E.


Book ID
127192280
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
568 KB
Volume
30
Category
Article
ISSN
0022-2623

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Tritiated platinum antitumor agents cont
โœ Steven D. Wyrick; Stephen G. Chaney ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 365 KB

Cis-diamminedichloroplatinum (11) (cisplatin) is one of the most widely used anticancer drugs today. However, platinum compounds possessing the 1,2-diaminocyclohexane (DACH) carrier ligand offer advantages over cisplatin with regard to bioavailability, activity and decreased renal toxicity. diaminoc