Comparative anatomy of the distribution of catecholamines within the inferior olivary complex from teleosts to primates

✍ Scribed by Ichiro Kamei; Sadao Shiosaka; Emiko Senba; Hiroshi Takagi; Masahiro Sakanaka; Shinobu Inagaki; Kenichi Takatsuki; Kunio Nakai; Harumichi Imai; Toru Itakura; Norihiko Komai; Masaya Tohyama

• Book ID: 102807907
• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: English
• Weight: 660 KB
• Volume: 202
• Category: Article
• ISSN: 0021-9967
• DOI: 10.1002/cne.902020111

✦ Synopsis

Abstract

The distribution of catecholamine (CA) in the inferior olivary complex (IO) of various vertebrate (from fish to monkey) was investigated by means of the histofluorescence technique. In addition, using rats, a further attempt was made to elucidate the origins of CA in the IO.

The IO of the lower vertebrates (from fish to birds) was in general poorly innervated by the CA neuron system. IO in the lower mammals, such as insectivora and bats, contained only a few CA nerve terminals, while that in the higher mammals such as rat, guinea pig, rabbit, cat, and monkey revealed quite a number. In these animals, species‐specific patterns of CA nerve terminals were found. In the rat, the highest concentration was observed in the dorsal lamella of the principal nucleus and in the guinea pig ventral lamella. In the rabbit and cat, maximum CA nerve terminals were detected in the dorsal accessory nucleus, while in the monkey, they were detected in the medial accessory nucleus.

The retrograde tracer technique of horseradish peroxidase (HRP) suggested that the main source of the abundant CA terminals in IO of the rat might be A~1~, A~2~, and A~3~ noradrenaline neurons, though not locus coeruleus and not dopaminergic ones.