𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparative Analysis of the Ligand-Binding Sites of the Metabotropic Glutamate Receptors mGluR1–mGluR8

✍ Scribed by M. S. Belenikin; I. I. Baskin; G. Costantino; V. A. Palyulin; R. Pellicciari; N. S. Zefirov

Book ID
110400062
Publisher
SP MAIK Nauka/Interperiodica
Year
2002
Tongue
English
Weight
487 KB
Volume
386
Category
Article
ISSN
1607-6729

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Localization of metabotropic glutamate r
Localization of metabotropic glutamate receptors mGluR1? and mGluR2/3 in the cat retina
✍ Cai, Wenhui; Pourcho, Roberta G. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 1009 KB

The distribution of metabotropic glutamate receptors 1␣ (mGluR1␣) and mGluR2/3 in the cat retina was studied through the use of preembedding immunocytochemistry for light and electron microscopy. Staining for mGluR1␣ in the outer plexiform layer was seen in numerous punctate structures that were ide

Immunocytochemical localization of the m
Immunocytochemical localization of the mGluR1b metabotropic glutamate receptor in the rat hypothalamus
✍ Mateos, Jos� Mar�a; Azkue, Jon; Ben�tez, Roc�o; Sarr�a, Rafael; Losada, Joaqu�n; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 611 KB

The mGluR1 metabotropic glutamate receptor is a G-protein-coupled receptor that exists as different C-terminal splice variants. When expressed in mammalian cells, the mGluR1 splice variants exhibit diverse transduction mechanisms and also slightly differ in their apparent agonist affinities. In the

Global physicochemical properties as act
Global physicochemical properties as activity discriminants for the mGluR1 subtype of metabotropic glutamate receptors
✍ Marta Filizola; Silvina M. Tasso; Gilda H. Loew; Hugo O. Villar 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB

## Abstract Metabotropic glutamate receptors (mGluRs) are important as candidate therapeutic targets for many neurological disorders. In the present work, the focus has been on the mGluR1 subtype, where agonists have a proconvulsant profile while antagonists exert anticonvulsant activity. Identific