Comparative analysis of chromatography peaks by computer and disc-integrator

✍ Scribed by Joanne F. Bernstein; Linda S. Chan; Stanley P. Azen; Ennis C. Layne; Paul J. Geiger

• Publisher: Elsevier Science
• Year: 1978
• Tongue: English
• Weight: 420 KB
• Volume: 85
• Category: Article
• ISSN: 0003-2697
• DOI: 10.1016/0003-2697(78)90246-4

✦ Synopsis

A reliability study was conducted to compare a new, computerized method of measuring the areas under chromatographic curves with the traditional hand method of determining the areas. Three runs of 30 separate injections of standard inorganic phosphate were made using the chromatographic and dry-ashing procedure developed in the laboratory of the Department of Pharmacology of the USC School of Medicine. Results indicate that there is no statistically significant difference between the traditional method and the new computer method for amounts greater than 10 nm, and the computer method is more precise for amounts less than 10 nm. Hence, great savings in time and an increase in precision can be made by using a computer for these analyses.