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Comparative Activity of Oral and Parenteral Topotecan in Murine Tumor Models: Efficacy of Oral Topotecan

✍ Scribed by McCabe, Francis L.; Johnson, Randall K.


Book ID
121460188
Publisher
Informa plc
Year
1994
Tongue
English
Weight
493 KB
Volume
12
Category
Article
ISSN
0735-7907

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## Abstract ## BACKGROUND Based on preclinical findings and on the clinical antitumor efficacy of sequential paclitaxel/topotecan and topotecan/etoposide, the authors sought to define the maximum tolerated doses (MTDs) and dose‐limiting toxicities (DLTs) associated with a sequential combination of