Comparaison of immunoturbidimetric and FPLC methods for the measurement of glycated hemoglobin A1c (HbA1c)

✍ Scribed by A. Bonin; L. Geoffroy; E.E. Delvin

• Publisher: Elsevier Science
• Year: 1995
• Tongue: English
• Weight: 123 KB
• Volume: 28
• Category: Article
• ISSN: 0009-9120
• DOI: 10.1016/0009-9120(95)91360-f

✦ Synopsis

Reml~ At a cut-off of 20 mg/L, the Ivfioral-Test showed a poor senmtivity (56%). Correction for creafininc did incresee the sensitivity (69%) for the same specificity (98.7"A). The beat screening performance was obtained when the I~emI-Te=t results were expressed as rate 0tg/min) with a recciver-o~ttor characteristic (ROC) curve area of 0.96. Conclusion Semi-qusatitativ,; determination of mieroalbuminuda on an ovemi#t tpecimen shows an inadequate sensitivity unless it is comoted for udue conecntrstion (ereetinine). A better serecning performance is obtained by using a timed specimen and calculatinn of micrcalbumin excretion rote.