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Comparable outcomes in fracture reduction and bone properties with RANKL inhibition and alendronate treatment in a mouse model of osteogenesis imperfecta

โœ Scribed by R. Bargman; R. Posham; A. L. Boskey; E. DiCarlo; C. Raggio; N. Pleshko

Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
893 KB
Volume
23
Category
Article
ISSN
0937-941X

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## Abstract Currently, the standard treatment for osteogenesis imperfecta (OI) is bisphosphonate therapy. Recent studies, however, have shown delayed healing of osteotomies in a subset of OI patients treated with such agents. The current study sought to determine the effects of another therapy, RAN