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Comorbidity between bipolar disorder and alcohol use disorder: Association of dopamine and serotonin gene polymorphisms

โœ Scribed by Baseer Yasseen; James L. Kennedy; Laurie A. Zawertailo; Usoa E. Busto

Book ID
116849746
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
147 KB
Volume
176
Category
Article
ISSN
0165-1781

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## Abstract Genetic linkage studies in bipolar disorder (BPD) suggest that a susceptibility locus exists on chromosome 18p11. The metallophosphoesterase (__MPPE1__) gene maps to this region. Dysregulation of protein phosphorylation and subsequent abnormal cellular signaling has been postulated to b