Community-based screening for Down's Syndrome in the first trimester using ultrasound and maternal serum biochemistry
β Scribed by Narelle C. Hadlow; Beverley G. Hewitt; Jan E. Dickinson; Peter Jacoby; Carol Bower
- Book ID
- 111161247
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 361 KB
- Volume
- 112
- Category
- Article
- ISSN
- 1470-0328
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Data on pregnancies with and without Down's syndrome between 10 and 14 weeks of pregnancy were used to determine the performance of combined ultrasound and biochemical markers in prenatal screening for Down's syndrome. We used three datasets: one published by on nuchal translucency measurement in 8
We have carried out a large retrospective study of -fetoprotein (AFP), free-human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein (PAPP-A) in the first trimester of pregnancy. Unlike other studies all women had routine ultrasound dating, carried out during a nuchal translucency