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Communications- Steroids and Related Natural Products. VI. Diborane Reduction of Lactones to Cyclic Hemiacetals

✍ Scribed by Pettit, George; Kasturi, T; Green, Brian; Knight, John


Book ID
127310148
Publisher
American Chemical Society
Year
1961
Tongue
English
Weight
246 KB
Volume
26
Category
Article
ISSN
0022-3263

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This is because the cyclic hemiacetal form engenders some flattering around the C-l,C-2,C-3 region which reduces van der Waals interactions due to the axial CH2Ph group; in the ringopened hydroxyaldehyde there is additional interaction between the axial CH2Ph group and adjacent quaternary centres. 9