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Common variatioins in the IL4R gene affect splicing and influence natural expression of the soluble isoform

✍ Scribed by Bergin, Ann Marie (author);Balder, Barbro (author);Kishore, Shivendra (author);Swärd, Kajsa (author);Hahn-Zoric, Mirjana (author);Löwhagen, Olle (author);Hanson, Lars Å (author);Padyukov, Leonid (author)

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 325 KB
Volume: 27
Category: Article
ISSN: 1059-7794
DOI: 10.1002/humu.20364

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Common variations in the IL4R gene affect splicing and influence natural expression of the soluble isoform

✍ Ann-Marie Bergin; Barbro Balder; Shivendra Kishore; Kajsa Swärd; Mirjana Hahn-Zo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB

We previously found the soluble interleukin 4 receptor (sIL4R) to be differently expressed in allergic asthma patients compared to healthy individuals. Here we present data demonstrating the involvement of the sequence variations, c.912-1003A > G, c.912-833T > C, c. 912-630A > G, and c.912-577A > G,