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Common non-synonymous polymorphisms in theBRCA1Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis

✍ Scribed by Xiang Huo; Zhibin Hu; Xiangjun Zhai; Yan Wang; Shui Wang; Xuechen Wang; Jianwei Qin; Wenseng Chen; Guangfu Jin; Jiyong Liu; Jun Gao; Qingyi Wei; Xinru Wang; Hongbing Shen

Publisher
Springer US
Year
2006
Tongue
English
Weight
216 KB
Volume
102
Category
Article
ISSN
0167-6806

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote