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Common MEFV mutation analysis in 36 Iranian patients with familial Mediterranean fever: clinical and demographic significance

โœ Scribed by Ali Bidari; Banafsheh Ghavidel-Parsa; Hossein Najmabadi; Elham Talachian; Majid Haghighat-Shoar; Behrooz Broumand; Babak Ghalehbaghi


Publisher
Springer
Year
2010
Tongue
English
Weight
195 KB
Volume
20
Category
Article
ISSN
1439-7595

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โœ Ruth Gershoni-Baruch; Ilana Kepten; Marwan Shinawi; Riva Brik ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 16 KB ๐Ÿ‘ 2 views

The MEFV gene involved in familial Mediterranean fever was recently cloned and four distinct sequence alterations (M680I, M694V, M694I and V726A) were identified at the 3'-most exon. We genotyped 170 unrelated FMF patients from various ethnic groups in Israel and found that mutation M694V predominat