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Common genetic variations of the cytochrome P450 1A1 gene and risk of hepatocellular carcinoma in a Chinese population

โœ Scribed by Rui Li; Yin Yao Shugart; Weiping Zhou; Yu An; Yuan Yang; Yun Zhou; Beibei Zhang; Daru Lu; Hongyang Wang; Ji Qian; Li Jin


Book ID
116429882
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
152 KB
Volume
45
Category
Article
ISSN
0959-8049

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The iso-enzyme pattern of cytochrome P450 was shown to be related to the development of chemically induced hepatocellular carcinoma (HCC) in rats, which is accelerated by chronic alcohol ingestion. Our study was designed to investigate the association of cytochrome P450 2E1 (CYP2E1) genetic polymorp