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Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations

✍ Scribed by Gesa M. Richter; Christian Graetz; Pia Pohler; Michael Nothnagel; Henrik Dommisch; Marja L. Laine; Mathias Folwaczny; Barbara Noack; Peter Eickholz; Birte Groessner-Schreiber; Søren Jepsen; Bruno G. Loos; Stefan Schreiber; Arne S. Schaefer

Book ID: 109361343
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 208 KB
Volume: 39
Category: Article
ISSN: 0303-6979
DOI: 10.1111/j.1600-051x.2011.01846.x

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote