Bernhard Steiner, ({ }^{1 \dagger}) Jonas Rosendahl, ({ }^{2 \dagger}) Heiko Witt, ({ }_{3}^{3}) Niels Teich, ({ }^{4}) Volker Keim, ({ }^{2}) Hans-Ulrich Schulz, ({ }^{5}) Roland Pfützer, ({ }^{6}) Matthias Löhr, ({ }^{7}) Thomas M. Gress, ({ }^{8}) Renate Nickel, ({ }^{9}) Olfert Landt, ({ }^{10}) Monika Koudova, ({ }^{11}) Milan Macek Jr, ({ }^{11}) Antoni Farre, ({ }^{12}) Teresa Casals, ({ }^{13}) Marie-Claire Desax, ({ }^{14}) Sabina Gallati, ({ }^{15}) Macarena Gomez-Lira, ({ }^{16}) Marie Pierre Audrezet, ({ }^{17}) Claude Férec, ({ }^{17}) Marie des Georges, ({ }^{18}) Mireille Claustres, ({ }^{18}) and Kaspar Truninger ({ }^{19 *})
({ }^{1}) Institute of Medical Genetics, University of Zurich, Schwerzenbach and Children's Hospital, Cantonal Hospital Lucerne, Lucerne, Switzerland; ({ }^{2}) Department of Gastroenterology and Hepatology, University of Leipzig, Leipzig, Germany; ({ }^{3}) Department of Gastroenterology and Hepatology, Charité, Campus Virchow-Klinikum, Berlin, Germany; ({ }^{4}) Internistische Gemeinschaftspraxis für Verdauungs- und Stoffwechselerkrankungen, Leipzig, Germany; ({ }^{5}) Department of Surgery, Otto-von-Guericke University, Magdeburg, Germany; ({ }^{6}) Division of Internal Medicine, Evangelisches Krankenhaus Kalk GmbH, Köln, Germany; 7 Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden; ({ }^{8}) Department of Gastroenterology, Endocrinology and Metabolisms, University of Marburg, Marburg, Germany; ({ }^{9}) Department of Pediatrics, Charité, Berlin, Germany; ({ }^{10}) TIB MOLBIOL GmbH, Berlin, Germany; "Department of Biology and Medical Genetics, Cystic Fibrosis Center, University Hospital Motol and Second Faculty of Medicine, Prague, Czech Republic; ({ }^{12}) Department of Gastroenterology, Hospital de la Santa Creu i S. Pau., Barcelona, Spain; ({ }^{13}) Medical and Molecular Genetics Center, IDIBELL, Barcelona, Spain; ({ }^{14}) Department of Internal Medicine, Cantonal Hospital Olten, Olten, Switzerland; ({ }^{15}) Department of Pediatrics, Division of Human Genetics, Inselspital, University of Bern, Bern, Switzerland; ({ }^{16}) Department of Life and Reproduction Sciences, Section Biology and Genetics, University of Verona, Italy; ({ }^{17}) Institute National de la Santé et de la Recherche Médicale (INSERM), Université de Bretagne Occidentale, Brest, France; ({ }^{18}) CHU Montpellier, Hôpital Arnaud de Villeneuve, Laboratoire de Génétique Moléculaire, Montpellier, France; INSERM, U827, Montpellier, France; Université Montpellier 1, UFR Médecine, Montpellier, France; ({ }^{19}) Clinic of Internal Medicine, SRO Hospital Langenthal, Langenthal, Switzerland