NMR studies on the flexibility of nucleo
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Y. Xu; A. Lecroisey; M. Veron; M. Delepierre; JoΓ«l Janin
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Article
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1997
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John Wiley and Sons
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English
β 66 KB
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Human NDP kinase B, product of the nm23-H2 gene, binds DNA. It has been suggested that a helix hairpin on the protein surface, part of the nucleotide substrate binding site, could accommodate DNA binding by swinging away. The presence of flexible regions was therefore investigated by 1 H NMR dynamic