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Comments on “The distribution of HIV-1 recombination breakpoints” by Jun Fan, Matteo Negroni, David L. Robertson

✍ Scribed by Gkikas Magiorkinis; Dimitrios Paraskevis; Angelos Hatzakis

Book ID: 104053212
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 145 KB
Volume: 8
Category: Article
ISSN: 1567-1348
DOI: 10.1016/j.meegid.2008.06.007

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The distribution of HIV-1 recombination

The distribution of HIV-1 recombination breakpoints

✍ Jun Fan; Matteo Negroni; David L. Robertson 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 564 KB

We find that recombination breakpoints are non-randomly distributed across the genomes of HIV-1 intersubtype recombinants. In particular we find two recombination prone regions, "hot spots", located approximately either side of the envelope gene. To investigate this, we test whether there is a corre