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Comment on “Ascertainment adjustment in complex diseases”

✍ Scribed by Michael P. Epstein

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
73 KB
Volume
23
Category
Article
ISSN
0741-0395

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✦ Synopsis

Glidden and Liang [2002] have raised important issues regarding ascertainment adjustment in the framework of variance-components modeling for complex genetic traits. While the structure of the authors' logistic variance-component model is simple, ascertainment issues arising with this model are likely analogous to ascertainment issues in more complex variance-component models commonly used for the analysis of either genetic disease data [

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