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Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: Individual patient data may be beneficial if only for a subset of trials

✍ Scribed by Sarah Donegan; Paula Williamson; Umberto D'Alessandro; Paul Garner; Catrin Tudur Smith

Book ID
115562115
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
336 KB
Volume
32
Category
Article
ISSN
0277-6715

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## Abstract ## Background The objective was to evaluate the efficacy and tolerability of donepezil (5 and 10 mg/day) compared with placebo in alleviating manifestations of mild to moderate Alzheimer's disease (AD). ## Method A systematic review of individual patient data from Phase II and III do