BACKGROUND. Turosteride (FCE 26073) is a new, potent, and selective 5␣-reductase inhibitor. We have investigated its effect on tumor growth, organ weight, and serum hormone levels in rats bearing the androgen sensitive Dunning R3327 prostatic carcinoma. METHODS. Animals with tumor diameters of 0.5-1
✦ LIBER ✦
Combined treatment of Dunning R3327 rat prostatic tumor with the 5α-reductase inhibitor PNU 157706 and the antiandrogen bicalutamide
✍ Scribed by Tiziana Zaccheo; Donata Giudici; Achille Panzeri; Enrico di Salle
- Book ID
- 105744785
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 175 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0344-5704
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## Background: Turosteride, a selective 5alpha-reductase inhibitor, was reported to be effective in inhibiting the growth of established tumors in the dunning r3327 rat prostatic carcinoma model. we evaluated the preventive effect of turosteride when administered during the latency period in this p