๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft

โœ Scribed by Huang, X; Lin, T; Gu, J; Zhang, L; Roth, J A; Stephens, L C; Yu, Y; Liu, J; Fang, B

Book ID
110039119
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
258 KB
Volume
9
Category
Article
ISSN
0969-7128

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Combination of oncolytic adenovirotherap
Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy
โœ Masayoshi Hioki; Shunsuke Kagawa; Toshiya Fujiwara; Ryo Sakai; Toru Kojima; Yuic ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 292 KB

## Abstract Cancer gene therapy and oncolytic virotherapy have been studied extensively. However, their clinical application is hampered by their weak anticancer activity. We previously constructed a replicating adenovirus (OBPโ€301, Telomelysin), in which the human telomerase reverse transcriptase

Bcl-xL antisense oligonucleotide and cis
Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts
โœ James E. Littlejohn; Xiaobo Cao; Steven D. Miller; Mustafa K. Ozvaran; Daniel Ju ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 702 KB

## Abstract Bclโ€xL functions as a dominant regulator of apoptotic cell death and is implicated in chemotherapeutic resistance of malignant pleural mesothelioma (MPM). Mesothelioma cell lines demonstrate increasing levels of Bclโ€xL as resistant clones are selected __invitro__. Moreover, upon introdu