The effects of the HMG CoA reductase inhibitors lovastatin and pravastatin on serum lipids, lipoproteins and apolipoproteins have been studied in 35 patients with primary hypercholesterolaemia. LDL cholesterol was lowered to the same extent by both agents compared on a mg basis of each drug per day.
Combined therapy with probucol and pravastatin in hypercholesterolaemia
β Scribed by K. Saku; B. Zhang; K. Hirata; Y. Okura; H. Bai; R. Liu; K. Arakawa
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 500 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The hypocholesterolaemic effect of pravastatin 40 mg and lovastatin 40 mg daily has been compared in patients with familial hypercholesterolaemia (FH). Administration of the two drugs was separated by a three-month washout period. The reduction in total serum cholesterol after 1,2 and 4 weeks of tre
The effects of the administration of slowrelease bezafibrate to hypercholesterolaemic patients who were already receiving long-term probucol treatment (mean 865 days, 500-1000 mg'day-1) were investigated. Bezafibrate was administered at either 200 tug'day 1 (13 males, 13 females, mean age 55.2 years
In order to determine whether there is a difference in the effect of the hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor pravastatin on cholesterol synthesis between the morning and the evening, we studied the 24-h profile of mevalonate in plasma and urine in 11 subjects with heter