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Combined therapy for thyroid squamous cell carcinoma

✍ Scribed by Filip Yves F. L. De Vos; Aniel Sewnaik; J. Hans W. de Wilt; Ernst J. Smid; Michael A. den Bakker; Esther van Meerten


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
549 KB
Volume
34
Category
Article
ISSN
1043-3074

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✦ Synopsis


Abstract

Background.

Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis.

Methods and Results.

We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy.

Conclusions.

Our patient now has a recurrence‐free survival of >20 months, longer than the mean survival described in the literature. Β© 2010 Wiley Periodicals, Inc. Head Neck, 2012


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