Combined therapy for thyroid squamous cell carcinoma
β Scribed by Filip Yves F. L. De Vos; Aniel Sewnaik; J. Hans W. de Wilt; Ernst J. Smid; Michael A. den Bakker; Esther van Meerten
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 549 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1043-3074
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β¦ Synopsis
Abstract
Background.
Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis.
Methods and Results.
We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy.
Conclusions.
Our patient now has a recurrenceβfree survival of >20 months, longer than the mean survival described in the literature. Β© 2010 Wiley Periodicals, Inc. Head Neck, 2012
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