Combined tests (p24 Ag and anti-HIV antibodies) during early HIV-1 infection
✍ Scribed by S Laperche; M Maniez-Montreuil; A.M Couroucé
- Book ID
- 117546159
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 104 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0399-077X
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## Abstract Murine monoclonal antibodies (Mabs) to the major core protein p24 of the human immunodeficiency virus type 1 (HIV‐1) were tested for their ability to inhibit the replication and spread __of__ the virus in permanent cell cultures (Molt4/8, K37, H9) and in the culture of 11‐2 stimulated T
The clinical utility of a flow cytometric assay (FCA) for intracellular HIV p24 antigen was evaluated in a group of HIV-1-infected subjects. A previously described method, p24-FCA (1), was modified to minimize nonspecific staining and to include irrelevant isotype-matched control antibodies. Blood m