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Combined radiation therapy and surgery in the management of advanced head and neck cancer: Final report of study 73–03 of the radiation therapy oncology group

✍ Scribed by Kramer, Simon ;Gelber, Richard D. ;Snow, James B. ;Marcial, Victor A. ;Lowry, Louis D. ;Davis, Lawrence W. ;Chandler, Richard


Publisher
Wiley (John Wiley & Sons)
Year
1987
Weight
870 KB
Volume
10
Category
Article
ISSN
0148-6403

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✦ Synopsis


Between March 1973 and June 1979, patients with advanced operable squamous cell carcinoma of the supraglottic larynx or hypopharynx were randomly allocated to receive either preoperative radiation therapy (5,000 rad) or postoperative radiation therapy (6,000 rad). Patients with oral cavity or oropharynx lesions were randomly assigned either preoperative radiation, postoperative radiation, or definitive radiation therapy (6,500-7,000 rad), with surgery reserved for salvage if residual disease was present 6 weeks after completion of irradiation. Three hundred twenty patients were evaluable with a median follow-up of 60 months. Based on results in 277 patients across all four re-Acknowledgments


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