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Combined mechanical and pharmacological approach to a thrombus-containing lesion

✍ Scribed by Itsik Ben-Dor; Augusto D. Pichard; Ron Waksman

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 417 KB
Volume: 75
Category: Article
ISSN: 1522-1946
DOI: 10.1002/ccd.22387

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✦ Synopsis

Abstract

Distal embolization during primary percutaneous coronary intervention for acute myocardial infarction is associated with impaired myocardial perfusion and poor outcome. Numerous pharmacological and mechanical strategies have been proposed to prevent and treat distal embolization. A successful combined mechanical and pharmacological approach to a large thrombus‐containing lesion in patients with acute coronary syndrome is described. A review of the current literature regarding the drugs and devices available for the prevention and treatment of large thrombus burden has also been performed. © 2010 Wiley‐Liss, Inc.

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