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Combined inhibitory effect of formestane and herceptin on a subpopulation of CD44+/CD24low breast cancer cells

✍ Scribed by Carla Cavaliere; Sara Corvigno; Mario Galgani; Gennaro Limite; Agostina Nardone; Bianca Maria Veneziani

Book ID
108586756
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
443 KB
Volume
101
Category
Article
ISSN
1347-9032

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✍ Yuhong Lu; Xiaolin Zi; Michael Pollak πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 450 KB

## Abstract The clinical usefulness of trastuzumab (Herceptin; Genentech, San Francisco, CA) in breast cancer treatment is limited by the rapid development of resistance. We previously reported that IGF‐I signaling confers resistance to the growth‐inhibitory actions of trastuzumab in a model system