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Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells

✍ Scribed by KUNTER, UTA; DANIEL, SOIZIC; ARVELO, MARIA B; CHOI, JEAN; SHUKRI, TALA; PATEL, VIRENDRA I; LONGO, CHRISTOPHER R; SCALI, SALVATORE T; SHRIKHANDE, GAUTAM; ROCHA, EDUARDO; CZISMADIA, EVA; MOTTLEY, CHRISTINA; GREY, SHANE T; FLOEGE, JÜRGEN; FERRAN, CHRISTIANE

Book ID
109067348
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
387 KB
Volume
68
Category
Article
ISSN
0085-2538

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## Abstract Inflammation induces the NF‐κB dependent protein A20 in human renal proximal tubular epithelial cells (RPTEC), which secondarily contains inflammation by shutting down NF‐κB activation. We surmised that inducing A20 without engaging the pro‐inflammatory arm of NF‐κB could improve outcom