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Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

✍ Scribed by Lauren A. Hirao; Ling Wu; Amir S. Khan; David A. Hokey; Jian Yan; Anlan Dai; Michael R. Betts; Ruxandra Draghia-Akli; David B. Weiner

Book ID
116960393
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
596 KB
Volume
26
Category
Article
ISSN
0264-410X

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## Abstract Therapeutic DNA vaccination is an attractive adjuvant option to conventional methods in the fight against cancer, like surgery radiotherapy and chemotherapy. Despite strong antitumor effects that were observed in small animals with different antigens, DNA‐based vaccines remain weakly im